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Showing posts with label HEALTH - BACK PAIN. Show all posts
Showing posts with label HEALTH - BACK PAIN. Show all posts

24 September 2014

BACK PAIN - When back pain could mean you've suffered a stroke in your spine






When back pain could mean you've suffered a stroke in your spine 


  • Michael Pell, 69, from Dartmoor, experienced excruciating pain in his back
  • The retired hairdresser had suffered a stroke in his spine that day in 2012
  • He still struggles to walk, and can no longer carry anything when moving

Michael Pell experienced a sudden, excruciating pain in his back
Michael Pell experienced a sudden, excruciating pain in his back
Tending to his much-loved garden one winter's morning, Michael Pell experienced a sudden, excruciating pain in his back, which left his legs feeling dead.
The pain came on suddenly and, initially, Michael, from Dartmoor, Devon, thought one of the deer that roam the remote area had kicked him.
'It was like nothing I'd ever felt before,' says Michael, 69, a retired hairdresser. 'I noticed I had no sensation from my lower back to my knees. When I realised it wasn't an animal, I thought it might be severe cramp, as I'd been working outside for four hours, mostly on my knees.
'I crawled 100 yards to our back door. I then pulled myself half up, but still had no feeling in the top half of my legs. My wife, Penny, had to help me to sit down.
'Although my feet and ankles worked, I had no control over my lower legs. I also had a burning sensation around my buttocks and down most of my legs.'
What Michael had suffered that day in January 2012 was a stroke, not to his brain, as usually happens, but his spine.
Normally, a stroke is caused either by a blockage to the blood supply to the brain, or a bleed from a weakened blood vessel supplying the brain. With a spinal stroke, the same principles apply, but the blockage or bleed affects the spinal cord.
Stretching from the base of the brain to the small of the back, the spinal cord is a key part of the body's central nervous system, which transmits instructions from the brain to the rest of the body.
Like the brain, the cord needs a constant blood supply to provide oxygen and nutrients. if it is halted, the nerves quickly become damaged and some die. As a result, these stop sending messages from the brain to the muscles - which muscles this affects depends on where the stroke occurs.
Scroll down for video 

    If a person has a stroke around the mid-section of their spinal cord, they may suffer paralysis in their legs, but everything above this will be unaffected. But a stroke around the neck section of the spinal cord could affect the muscles in the arms.
    The most common cause of spinal strokes, as with brain strokes, is a build-up of cholesterol plaque in an artery wall, which then blocks it. Alternatively, small vessels supplying the spine rupture, due to abnormalities of the vessel walls or malformations of the vessels, says Tony Rudd, professor of stroke medicine at London's King's College Hospital.
    Some patients have a spinal stroke during surgery, for example, while treating an aneurysm, a bulge in a blood vessel, especially if it's in the aorta in the abdomen. A stent, or hollow tube, is usually inserted into the aorta to strengthen its wall. This temporarily blocks blood flow to the spine, so the risk of a spinal stroke increases.
    What Michael had suffered that day in January 2012 was a stroke in his spine
    What Michael had suffered that day in January 2012 was a stroke in his spine
    'Obesity or smoking are also causes, as fatty deposits make arteries narrow and raise blood pressure, putting strain on the body,' says Professor Rudd. 'Normally, there is no warning: only in rare cases do patients experience a slight weakness in their legs briefly beforehand.' Of the 152,000 strokes in the UK each year, spinal strokes make up about 1.25 per cent, says the Stroke Association.
    For some, 'a spinal stroke can prove fatal towards the neck, as it can have a devastating impact on nerves to muscles, which control breathing and the diaphragm', says Professor Rudd. most spinal stroke victims will survive, but are often left with life-long disabilities. 'Unfortunately, the prognosis for spinal stroke patients is not great,' says Professor Rudd.
    While other parts of the brain are able to take over other functions in brain stroke patients, once the wires are cut in the spinal cord, there's no route for sensory messages. 
    My right leg still feels dead above the knee. I can stick a pin in it and don't feel anything. But, if our cat's tail lightly touches my bare leg, it's like an electric shock 
    Treatments include reducing the pressure of the cerebrospinal fluid, a clear liquid found in the cavities around the brain and spinal cord. Following spinal stroke, this can build up around where it struck. Draining some, via a lumbar puncture in the lower back, can reduce pressure, improving blood flow. 'Otherwise, the only treatment is rehabilitation through physiotherapy and exercise,' says Professor Rudd.
    Alex Rankin, director of services at spinal injury charity Aspire, says spinal strokes bring different problems in different patients.
    'Most people think of not being able to walk, but there can be loss of bladder and bowel function due to nerve damage, or skin issues including pressure sores, as they have lost their sense of touch.
    'Most people cannot sweat below the level of their injury, so are more likely to overheat. they also face circulation issues and so are more likely to feel the cold. There can be pain issues, too.'
    It can lead to fatal complications if the patient is left paralysed.
    'Being more immobile puts patients at risk of pneumonia, caused by an infection in the lungs, and bladder infections. if they're lying for long periods, bed sores that become infected and lead to septicaemia - potentially fatal blood poisoning - become a concern,' says Professor Rudd.
    Michael Pell had no idea of such risks when he suffered his spinal stroke: he thought he'd suffered a minor back injury, and even had lunch afterwards, although the 'deadness' in his legs and burning sensation remained.
    Michael still struggles to walk, as he is so unsteady
    Michael still struggles to walk, as he is so unsteady
    Later that afternoon, he called NHS Direct, who recommended going to A&E. He underwent various examinations, but, initially, the cause was unclear. Spinal stroke can be hard to detect, and common causes of numbness in the legs are often explored first.
    As the numbness in Michael's legs meant he'd lost control of his bowels and bladder, he stayed in hospital for further tests.
    A week later, possible causes such as a slipped disc, trapped nerve, severe inflammation, or a tumour had been ruled out.
    Because of continued weakness in his legs, he had an MRI scan of his spine, and spinal stroke was diagnosed. 'I'd never heard of it, but was relieved this stroke allowed me to function and talk,' says Michael, who, despite being a light social drinker and smoker, had been fit and active.
    He remained in hospital for two weeks, where full feeling to his left leg and his ability to control going to the toilet returned. He learned to walk again using a Zimmer frame, before using a walking stick for a few months, while undergoing rehabilitation and physiotherapy.
    Michael now takes daily medicines, including blood-thinning pills and cholesterol-lowering statins, to ward off stroke, and gabapentin, for long-term nerve damage, to dampen the burning sensation in his right leg. 'If I forget to take it, it's like I'm standing next to our Aga cooker,' he says.
    'My right leg still feels dead above the knee. I can stick a pin in it and don't feel anything. But, if our cat's tail lightly touches my bare leg, it's like an electric shock. The nerves are so damaged, they act in an unusual way - the lighter the touch, the greater the sensation, it seems.'
    Michael still struggles to walk, as he is so unsteady. He can no longer carry anything when moving. He continues to be a keen gardener, but uses a ride-on mower. He can't bend down easily, so he lies on the ground for less arduous tasks.
    'My consultant said if feeling didn't return within 18 months, it never would. So, I've accepted I'll always walk with my leg dragging behind me,' says Michael.
    'But I haven't let it stop me, and it has made me appreciate more what I can achieve in the garden.'
    ngs.org.uk



    Source: http://www.dailymail.co.uk/



    3 March 2014

    BACK PAIN - 8 Bad Habits That Cause Back Pain









    It is not always necessity to think about different illnesses and conditions when you have a back pain. Even healthiest individuals can experience this discomforts in everyday life. Read the article and you may be a bit surprised about some causes of your back pain.
    Sleeping on an old mattress
    A good mattress lasts eight to ten years. If you have not replaced yours for more than 10 years chances are that your spine is not getting the support it needs. Replace your old one with mattress that is not too hard and even not too soft. The curves of your back won’t sink in and won’t offer enough support.
    Carrying a huge bag
    If you are someone who likes to carry around your home, your back won’t be grateful. Carrying a heavy bag on a side of your shoulder causes your body to become imbalanced, getting your spine out of balance too. Switch to a lighter bag. Your purse with everything in it should weigh no more than ten percent of your body weight.


    Wearing stilettos or flats
    Heels which are too high for you force you to arch your back, putting stress on your joints. Flats can be bad for you as well, depending on your foot type. Sandals without a supportive back do damage, causing your feet to move from side to side and distributing your body weight unevenly. Everyone has an ideal heel height. Find yours.
    Holding a grudge
    Researchers at one university found that people who practice forgiveness experience fewer feelings of resentment, depression, anger and fewer aches and pains. Your emotions, muscle tension and thoughts can directly influence the strength of your pain signals. Not only are grudges bad for you physically, they do not do much for you emotionally either.
    Sitting all day
    Bad news for all of you with a desk job! It is bad for your health. Sitting around all day may feel nice, but most of you do not maintain proper posture while sitting in front of a computer all day, causing weakness of back muscles because of inactivity. Sitting also puts 50 percent more pressure on your spine than standing does. If your office does not get you a standing desk to help keep your core and back muscles engaged all the time, lean back throughout your day so you are sitting at a 130 degree angle to reduce compression of the discs in the spine. Finally, be sure your head is straight, not straining forward, when using the comp.
    Stressing out
    If you are stressed out, your whole body is also stressed including the muscles in your neck and back that contract and clench up. And if you keep stressing, those tight muscles do not get a chance to relax, causing pain. There are a lot of proven ways to lower your stress levels including exercise, meditation and a warm bath.
    Skipping workouts
    Exercise builds muscle tone that is vital for supporting your back. When you do not get enough of it, you experience stiffness, weakened muscles and your spinal discs become degenerated. Workouts that strengthen the back and abdomen are your best choice.
    Eating too much junk food
    Not surprisingly, an intake of high calorie and low nutrient food leads to weight gain. That weight gain can put a load on your back. Excess weight around the midsection causes the pelvis to pull forward, creating stress for the back. Overweight individuals are at an increased risk of osteoarthritis. Dropping even 5 to 10 percent of your body weight can improve your back condition.
    Source: http://www.fitnea.com

    12 June 2013

    HEALTH - Back Pain















    By Mayo Clinic staff

    Definition

    Back pain is a common complaint. Most people in the United States will experience low back pain at least once during their lives. Back pain is one of the most common reasons people go to the doctor or miss work.
    On the bright side, you can take measures to prevent or lessen most back pain episodes. If prevention fails, simple home treatment and proper body mechanics will often heal your back within a few weeks and keep it functional for the long haul. Surgery is rarely needed to treat back pain.

    Symptoms

    Symptoms of back pain may include:
    • Muscle ache
    • Shooting or stabbing pain
    • Pain that radiates down your leg
    • Limited flexibility or range of motion of the back
    • Inability to stand up straight
    When to see a doctor
    Most back pain gradually improves with home treatment and self-care. Although the pain may take several weeks to disappear completely, you should notice some improvement within the first 72 hours of self-care. If not, see your doctor.
    In rare cases, back pain can signal a serious medical problem. Seek immediate care if your back pain:
    • Causes new bowel or bladder problems
    • Is associated with pain or throbbing (pulsation) in the abdomen, or fever
    • Follows a fall, blow to your back or other injury
    Contact a doctor if your back pain:
    • Is constant or intense, especially at night or when you lie down
    • Spreads down one or both legs, especially if the pain extends below the knee
    • Causes weakness, numbness or tingling in one or both legs
    • Is accompanied by unexplained weight loss
    • Occurs with swelling or redness on your back
    Also, see your doctor if you start having back pain for the first time after age 50, or if you have a history of cancer, osteoporosis, steroid use, or drug or alcohol abuse.

    Causes

    Back pain often develops without a specific cause that your doctor can identify with a test or imaging study. Conditions commonly linked to back pain include:
    • Muscle or ligament strain.Repeated heavy lifting or a sudden awkward movement may strain back muscles and spinal ligaments. If you're in poor physical condition, constant strain on your back may cause painful muscle spasms.
    • Bulging or ruptured disks. Disks act as cushions between the individual bones (vertebrae) in your spine. Sometimes, the soft material inside a disk may bulge out of place or rupture and press on a nerve. The presence of a bulging or ruptured disk on an X-ray doesn't automatically equal back pain, though. Disk disease is often found incidentally; many people who don't have back pain turn out to have bulging or ruptured disks when they undergo spine X-rays for some other reason.
    • Arthritis. Osteoarthritis can affect the lower back. In some cases, arthritis in the spine can lead to a narrowing of the space around the spinal cord, a condition called spinal stenosis.
    • Skeletal irregularities. Back pain can occur if your spine curves in an abnormal way. Scoliosis, a condition in which your spine curves to the side, also may lead to back pain, but generally only if the scoliosis is quite severe.
    • Osteoporosis. Compression fractures of your spine's vertebrae can occur if your bones become porous and brittle.

    Risk factors

    Anyone can develop back pain, even children and teens. Although excess weight, lack of exercise and improper lifting are often blamed for back pain, research looking at these possible risk factors hasn't yet provided any clear-cut answers.
    One group that does appear to have a greater risk of back pain are people with certain psychological issues, such as depression and anxiety, though the reasons why there's an increased risk aren't known.

    Preparing for your appointment

    If you have back pain that's lasted for at least a few days and isn't improving, make an appointment with your family doctor or primary care provider.
    Here's some information to help you prepare for your appointment and what to expect from your doctor.
    What you can do
    • Write down key personal information, including any mental or emotional stressors in your life.
    • Make a list of your key medical information, including any other conditions for which you're being treated and the names of any medications, vitamins or supplements you're taking.
    • Note any recent injuries that may have damaged your back.
    • Take a family member or friend along, if possible. Someone who accompanies you may remember something that you missed or forgot.
    • Write down questions to ask your doctor. Creating your list of questions in advance can help you make the most of your time with your doctor.
    For back pain, some basic questions to ask your doctor include:
    • What is the most likely cause of my back pain?
    • Do I need any diagnostic tests?
    • What treatment approach do you recommend?
    • If you're recommending medications, what are the possible side effects?
    • I have other medical conditions. How can I best manage these conditions together?
    • How long will I need treatment?
    • What self-care measures should I be taking?
    • Is there anything else I can do to help prevent a recurrence of back pain?
    What to expect from your doctorYour doctor is likely to ask you a number of questions. Being ready to answer them may reserve time to go over any points you want to spend more time on. Your doctor may ask:
    • When did you first begin having back pain?
    • How often do you have back pain?
    • How much is your pain limiting your ability to function?
    • Do you have any other signs or symptoms in addition to back pain?
    • Do you do heavy physical work?
    • Do you exercise regularly? If yes, with what types of activities?
    • How often do you feel blue or depressed?
    • How much stress or conflict do you experience on a daily basis?
    • Do you sleep well most of the time?
    • What treatments or self-care measures have you tried so far? Has anything helped?
    • Are you currently being treated or have you recently been treated for any other medical conditions?
    What you can do in the meantimeWhile you're waiting for your appointment, you may benefit from applying heat, such as with a heating pad or hot bath, for short periods of time to improve blood flow to the area and relax the muscles. Be careful not to sleep with a heating pad on, as this can cause burns. The application of cold with an ice or cold gel pack can also provide back pain relief. Choose whichever — hot or cold — gives you the most relief.
    Try to keep to your normal activities as much as possible, unless your work normally requires heavy lifting. If a particular activity increases your pain, stop doing that activity.

    Tests and diagnosis

    Diagnostic tests aren't usually necessary to confirm the cause of your back pain. However, if you do see your doctor for back pain, he or she will examine your back and assess your ability to sit, stand, walk and lift your legs. Your doctor may also test your reflexes with a rubber reflex hammer.
    These assessments help determine where the pain comes from, how much you can move before pain forces you to stop and whether you have muscle spasms. They will also help rule out more-serious causes of back pain.
    If there is reason to suspect a specific condition may be causing your back pain, your doctor may order one or more tests:
    • X-ray. These images show the alignment of your bones and whether you have arthritis or broken bones. X-ray images won't directly show problems with your spinal cord, muscles, nerves or disks.
    • Magnetic resonance imaging (MRI) or computerized tomography (CT) scans. These scans can generate images that may reveal herniated disks or problems with bones, muscles, tissue, tendons, nerves, ligaments and blood vessels.
    • Bone scan. In rare cases, your doctor may use a bone scan to look for bone tumors or compression fractures caused by osteoporosis.
    • Nerve studies (electromyography, or EMG). This test measures the electrical impulses produced by the nerves and the responses of your muscles. This test can confirm nerve compression caused by herniated disks or narrowing of your spinal canal (spinal stenosis).

    Treatments and drugs

    Most back pain gets better with a few weeks of home treatment and careful attention. Over-the-counter pain relievers may be all that you need to improve your pain. A short period of bed rest is OK, but more than a couple of days actually does more harm than good. Continue your daily activities as much as you can tolerate. Light activity, such as walking and daily activities of living, is usually OK. But, if an activity increases your pain, stop doing that activity. If home treatments aren't working after several weeks, your doctor may suggest stronger medications or other therapies.
    MedicationsYour doctor is likely to recommend pain relievers such as acetaminophen (Tylenol, others) or nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil, Motrin, others) or naproxen (Aleve). Both types of medications are effective at relieving back pain. Take these medications as directed by your doctor, because overuse can cause serious side effects. If mild to moderate back pain doesn't get better with over-the-counter pain relievers, your doctor may also prescribe a muscle relaxant. Muscle relaxants can cause dizziness and may make you very sleepy.
    Narcotics, such as codeine or hydrocodone, may be used for a short period of time with close supervision by your doctor.
    Low doses of certain types of antidepressants — particularly tricyclic antidepressants, such as amitriptyline — have been shown to relieve chronic back pain, independent of their effect on depression.
    EducationRight now, there's no commonly accepted program to teach people with back pain how to manage the condition effectively. That means education may be a class, a talk with your doctor, written material or a video. What's important is that education emphasizes the importance of staying active, reducing stress and worry, and teaching ways to avoid future injury. However, it's also important for your doctor to explain that your back pain may recur, especially during the first year after the initial episode, but that the same self-care measures will be able to help again.
    Physical therapy and exercisePhysical therapy is the cornerstone of back pain treatment. A physical therapist can apply a variety of treatments, such as heat, ultrasound, electrical stimulation and muscle-release techniques, to your back muscles and soft tissues to reduce pain. As pain improves, the therapist can teach you specific exercises that may help increase your flexibility, strengthen your back and abdominal muscles, and improve your posture. Regular use of these techniques can help prevent pain from returning.
    InjectionsIf other measures don't relieve your pain and if your pain radiates down your leg, your doctor may inject cortisone — an anti-inflammatory medication — into the space around your spinal cord (epidural space). A cortisone injection helps decrease inflammation around the nerve roots, but the pain relief usually lasts less than a few months.
    In some cases, your doctor may inject numbing medication and cortisone into or near the structures believed to be causing your back pain, such as the facet joints of the vertebrae. Located on the sides, top and bottom of each vertebra, these joints connect the vertebrae to one another and stabilize the spine while still allowing flexibility.
    SurgeryFew people ever need surgery for back pain. If you have unrelenting pain associated with radiating leg pain or progressive muscle weakness caused by nerve compression, you may benefit from surgical intervention. Otherwise, surgery usually is reserved for pain related to structural anatomical problems that haven't responded to intensive conservative therapy measures.

    Alternative medicine

    A number of alternative treatments are available that may help ease symptoms of back pain. Always discuss the benefits and risks with your doctor before starting any new alternative therapy.
    • Chiropractic care. Back pain is one of the most common reasons that people see a chiropractor.
    • Acupuncture. A practitioner of acupuncture inserts sterilized stainless steel needles into the skin at specific points on the body. Some people with low back pain report that acupuncture helps relieve their symptoms.
    • Massage. If your back pain is caused by tense or overworked muscles, massage therapy may help.
    • Yoga. There are several types of yoga, a broad discipline that involves practicing specific postures or poses, breathing exercises and relaxation techniques. Results of a few clinical trials suggest that yoga offers some benefit for people with back pain.

    Prevention

    You may be able to avoid back pain by improving your physical condition and learning and practicing proper body mechanics.
    To keep your back healthy and strong:
    • Exercise. Regular low-impact aerobic activities — those that don't strain or jolt your back — can increase strength and endurance in your back and allow your muscles to function better. Walking and swimming are good choices. Talk with your doctor about which activities are best for you.
    • Build muscle strength and flexibility. Abdominal and back muscle exercises (core-strengthening exercises) help condition these muscles so that they work together like a natural corset for your back. Flexibility in your hips and upper legs aligns your pelvic bones to improve how your back feels. Your doctor or physical therapist can let you know which exercises are right for you.
    • Maintain a healthy weight. Being overweight puts strain on your back muscles. If you're overweight, trimming down can prevent back pain.
    Use proper body mechanics:
    • Stand smart. Maintain a neutral pelvic position. If you must stand for long periods of time, alternate placing your feet on a low footstool to take some of the load off your lower back. Good posture can reduce the amount of stress placed on back muscles.
    • Sit smart. Choose a seat with good lower back support, arm rests and a swivel base. Consider placing a pillow or rolled towel in the small of your back to maintain its normal curve. Keep your knees and hips level. Change your position frequently, ideally at least once every half hour.
    • Lift smart. Let your legs do the work. Move straight up and down. Keep your back straight and bend only at the knees. Hold the load close to your body. Avoid lifting and twisting simultaneously. Find a lifting partner if the object is heavy or awkward. Learning to lift properly may be more effective at preventing a recurrence of back pain than a first episode.
    Buyer bewareBecause back pain is such a common problem, there are numerous products available that promise to prevent or relieve your back pain. But, there's no definitive evidence that special shoes, shoe inserts, back supports, specially designed furniture or stress management programs can help. In addition, there doesn't appear to be one type of mattress that's best for people with back pain. It's probably a matter of what feels most comfortable to you.

    12 April 2013

    HEALTH INFO - Spinal Cord Injury

    From Wikipedia, the free encyclopedia






    spinal cord injury (SCI) refers to any injury to the spinal cord that is caused by trauma instead of disease. Depending on where the spinal cord and nerve roots are damaged, the symptoms can vary widely, from pain to paralysis to incontinence.Spinal cord injuries are described at various levels of "incomplete", which can vary from having no effect on the patient to a "complete" injury which means a total loss of function.
    Treatment of spinal cord injuries starts with restraining the spine and controlling inflammation to prevent further damage. The actual treatment can vary widely depending on the location and extent of the injury. In many cases, spinal cord injuries require substantial physical therapy and rehabilitation, especially if the patient's injury interferes with activities of daily life.

    Spinal cord injuries have many causes, but are typically associated with major trauma from motor vehicle accidentsfallssports injuries, and violence. Research into treatments for spinal cord injuries includes controlledhypothermia and stem cells, though many treatments have not been studied thoroughly and very little new research has been implemented in standard care.



    Classification


    The American Spinal Injury Association (ASIA) first published an international classification of spinal cord injury in 1982, called theInternational Standards for Neurological and Functional Classification of Spinal Cord Injury. Now in its sixth edition, the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI) is still widely used to document sensory and motor impairments following SCI.[4] It is based on neurological responses, touch and pinprick sensations tested in each dermatome, and strength of ten key muscles on each side of the body, including hip flexion (L2), shoulder shrug (C4), elbow flexion (C5), wrist extension (C6), and elbow extension (C7).[5] Traumatic spinal cord injury is classified into five categories on the ASIA Impairment Scale:

    • A indicates a "complete" spinal cord injury where no motor or sensory function is preserved in the sacral segments S4-S5.
    • B indicates an "incomplete" spinal cord injury where sensory but not motor function is preserved below the neurological level and includes the sacral segments S4-S5. This is typically a transient phase and if the person recovers any motor function below the neurological level, that person essentially becomes a motor incomplete, i.e. ASIA C or D.
    • C indicates an "incomplete" spinal cord injury where motor function is preserved below the neurological level and more than half of key muscles below the neurological level have a muscle grade of less than 3, which indicates active movement with full range of motion against gravity.
    • D indicates an "incomplete" spinal cord injury where motor function is preserved below the neurological level and at least half of the key muscles below the neurological level have a muscle grade of 3 or more.
    • E indicates "normal" where motor and sensory scores are normal. Note that it is possible to have spinal cord injury and neurological deficits with completely normal motor and sensory scores.[4]

    Dimitrijevic[6] proposed a further class, the so-called discomplete lesion, which is clinically complete but is accompanied by neurophysiological evidence of residual brain influence on spinal cord function below the lesion.






    The spinal cord (highlighted in dark red) runs from the base of the brain down through 
    the spine in a person's back. It connects the brain to the nerves throughout the body.





    Signs and symptoms

    Signs recorded by a physician and symptoms experienced by a patient will vary depending on where the spine is injured and the extent of the injury. These are all determined by the area of the body that the injured area of the spine innervates. A section of skin innervatedthrough a specific part of the spine is called a dermatome, and spinal injury can cause pain, numbness, or a loss of sensation in the relevant areas. A group of muscles innervated through a specific part of the spine is called a myotome, and injury to the spine can cause problems with voluntary motor control. The muscles may contract uncontrollably, become weak, or be completely unresponsive. The loss of muscle function can have additional effects if the muscle is not used, including atrophy of the muscle and bone degeneration.

    A severe injury may also cause problems in parts of the spine below the injured area. In a "complete" spinal injury, all function below the injured area are lost. In an "incomplete" injury, some or all of the functions below the injured area may be unaffected. If the patient has the ability to contract the anal sphincter voluntarily or to feel a pinprick or touch around the anus, the injury is considered to be incomplete. The nerves in this area are connected to the very lowest region of the spine, the sacral region, and retaining sensation and function in these parts of the body indicates that the spinal cord is only partially damaged. An incomplete spinal cord injury involves preservation of motor or sensory function below the level of injury in the spinal cord.[8] This includes a phenomenon known as sacral sparing which involves the preservation of cutaneous sensation in the sacraldermatomes, even though sensation is impaired in the thoracic and lumbar dermatomes below the level of the lesion.[9] Sacral sparing may also include the preservation of motor function (voluntary external anal sphincter contraction) in the lowest sacral segments.[8] Sacral sparing has been attributed to the idea that the sacral spinal pathways are not as likely as the other spinal pathways to become compressed after injury.[9] The sparing of the sacral spinal pathways can be attributed to the lamination of fibers within the spinal cord.[9]

    A complete injury frequently means that the patient has little hope of functional recovery.[citation needed] The relative incidence of incomplete injuries compared to complete spinal cord injury has improved over the past half century, due mainly to the emphasis on better initial care and stabilization of spinal cord injury patients.[10] Most patients with incomplete injuries recover at least some function.[citation needed]

    In addition to sensation and muscle control, the loss of connection between the brain and the rest of the body can have specific effects depending on the location of the injury.

    Determining the exact "level" of injury is critical in making accurate predictions about the specific parts of the body that may be affected by paralysis and loss of function. The level is assigned according to the location of the injury by the vertebra of the spinal column. While the prognosis of complete injuries are generally predictable since recovery is rare, the symptoms of incomplete injuries can vary and it is difficult to make an accurate prediction of the outcome.



        

    Segmental Spinal Cord Level and Function
    LevelFunction
    C1-C6Neck flexors
    C1-T1Neck extensors
    C3,C4,C5Supply diaphragm (mostly C4)
    C5,C6Shoulder movement, raise arm (deltoid); flexion of elbow (biceps); C6 externally rotates the arm (supinates)
    C6,C7Extends elbow and wrist (triceps and wristextensors); pronates wrist
    C7,T1Flexes wrist
    C7,T1Supply small muscles of the hand
    T1-T6Intercostals and trunk above the waist
    T7-L1Abdominal muscles
    L1,L2,L3,L4Thigh flexion
    L2,L3,L4Thigh adduction
    L4,L5, S1Thigh abduction
    L5,S1, S2Extension of leg at the hip (gluteus maximus)
    L2,L3,L4Extension of leg at the knee (quadriceps femoris)
    L4,L5,S1,S2Flexion of leg at the knee (hamstrings)
    L4,L5,S1Dorsiflexion of foot (tibialis anterior)
    L4,L5,S1Extension of toes
    L5,S1,S2Plantar flexion of foot
    L5,S1,S2Flexion of toes



    Cervical

    Cervical (neck) injuries usually result in full or partial tetraplegia (Quadriplegia). However, depending on the specific location and severity of trauma, limited function may be retained.
    • Injuries at the C-1/C-2 levels will often result in loss of breathing, necessitating mechanical ventilators or phrenic nerve pacing.
    • C3 vertebrae and above : Typically results in loss of diaphragm function, necessitating the use of a ventilator for breathing.
    • C4 : Results in significant loss of function at the biceps and shoulders.
    • C5 : Results in potential loss of function at the shoulders and biceps, and complete loss of function at the wrists and hands.
    • C6 : Results in limited wrist control, and complete loss of hand function.
    • C7 and T1 : Results in lack of dexterity in the hands and fingers, but allows for limited use of arms.
    Patients with complete injuries above C7 typically cannot handle activities of daily living and cannot function independently.[citation needed]
    Additional signs and symptoms of cervical injuries include:

    Thoracic
    Complete injuries at or below the thoracic spinal levels result in paraplegia. Functions of the hands, arms, neck, and breathing are usually not affected.
    • T1 to T8 : Results in the inability to control the abdominal muscles. Accordingly, trunk stability is affected. The lower the level of injury, the less severe the effects.
    • T9 to T12 : Results in partial loss of trunk and abdominal muscle control.
    Typically lesions above the T6 spinal cord level can result in Autonomic Dysreflexia.[11]


    Lumbosacral

    The effects of injuries to the lumbar or sacral regions of the spinal cord are decreased control of the legs and hips, urinary system, and anus.
    • Bowel and bladder function is regulated by the sacral region of the spine. In that regard, it is very common to experience dysfunction of the bowel and bladder, including infections of the bladder and anal incontinence, after traumatic injury.
    • Sexual function is also associated with the sacral spinal segments, and is often affected after injury. During a psychogenicsexual experience, signals from the brain are sent to the sacral parasympathetic cell bodies at spinal levels S2-S4 and in case of men, are then relayed to the penis where they trigger an erection. A spinal cord lesion of descending fibers to levels S2-S4 could, therefore, potentially result in the loss of psychogenic erection. A reflexogenic erection, on the other hand, occurs as a result of direct physical contact to the penis or other erotic areas such as the ears, nipples or neck, and thus not involving descending fibers from the brain. A reflex erection is involuntary and can occur without sexually stimulating thoughts. The nerves that control a man's ability to have a reflex erection are located in the sacral nerves (S2-S4) of the spinal cord and could be affected after a spinal cord injury at this level.[12][13][14]

    [edit]Other syndromes of incomplete injury

    Central cord syndrome is a form of incomplete spinal cord injury characterized by impairment in the arms and hands and, to a lesser extent, in the legs. This is also referred to as inverse paraplegia, because the hands and arms are paralyzed while the legs and lower extremities work correctly.
    Most often the damage is to the cervical or upper thoracic regions of the spinal cord, and characterized by weakness in the arms with relative sparing of the legs with variable sensory loss.
    This condition is associated with ischemia, hemorrhage, or necrosis involving the central portions of the spinal cord (the large nerve fibers that carry information directly from the cerebral cortex). Corticospinal fibers destined for the legs are spared due to their more external location in the spinal cord.
    Ischemia of the spinal cord is reduced blood flow to the spinal cord which is supplied by the anterior spinal artery and the paired posterior spinal arteries. This condition may be associated with arterioscleorosis, trauma, emboli, diseases of the aorta, and other disorders. Prolonged ischemia may lead to infarction of the spinal cord tissue.[15] Ischemia of the spinal cord affects its function and can lead to muscle weakness and paralysis. The spinal cord may also suffer circulatory impairment if the segmental medullary arteries, particularly the great anterior segmental medullary artery are narrowed by obstructive arterial disease. When systemic blood pressure drops severely for 3-6 min, blood flow from the segmental medullary arteries to the anterior spinal artery supplying the midthoracic region of the spinal cord may be reduced or stopped. These people may also lose sensation and voluntary movement in the areas supplied by the affected level of the spinal cord. [16]
    This clinical pattern may emerge during recovery from spinal shock due to prolonged swelling around or near the vertebrae, causing pressures on the cord. The symptoms may be transient or permanent.
    Anterior cord syndrome is often associated with flexion type injuries to the cervical spine, causing damage to the anterior portion of the spinal cord and/or the blood supply from the anterior spinal artery.[17] Below the level of injury motor function, pain sensation, and temperature sensation are lost. While touch, proprioception (sense of position in space), and sense of vibration remain intact.
    Posterior cord syndrome can also occur, but is very rare. Damage to the posterior portion of the spinal cord and/or interruption to the posterior spinal artery causes the loss of proprioception and epicritic sensation (e.g.: stereognosis, graphesthesia) below the level of injury.[17] Motor function, sense of pain, and sensitivity to light touch remain intact.[17]
    Brown-Séquard syndrome usually occurs when the spinal cord is hemisectioned or injured on the lateral side. True hemisections of the spinal cord are rare, while partial lesions due to penetrating wounds (e.g.: gunshot wounds or knife penetrations) are more common.[17] On the ipsilateral side of the injury (same side), there is a loss of motor function, proprioception, vibration, and light touch. Contralaterally (opposite side of injury), there is a loss of pain, temperature, and crude touch sensations.
    Tabes Dorsalis results from injury to the posterior part of the spinal cord, usually from infection diseases such as syphilis, causing loss of touch and proprioceptive sensation.
    Conus medullaris syndrome results from injury to the tip of the spinal cord, located at L1 vertebra.

    Causes


    Spinal cord injuries are most often traumatic, caused by lateral bending, dislocation, rotation, axial loading, and hyperflexion or hyperextension of the cord or cauda equinaMotor vehicle accidents are the most common cause of SCIs, while other causes includefalls, work-related accidents, sports injuries, and penetrations such as stab or gunshot wounds.[18] SCIs can also be of a non-traumatic origin, as in the case of cancer, infection, intervertebral disc disease, vertebral injury and spinal cord vascular disease.[19]

    Men are at more risk for spinal cord injury than women.[20][21] More than 80% of the spinal cord injury patients are men.




    Diagnosis


    A radiographic evaluation using a x-rayMRI or CT scan can determine if there is any damage to the spinal cord and where it is located. A neurologic evaluation incorporating sensory testing and reflex testing can help determine the motor function of a person with a SCI.



    Management




    Modern trauma care includes a step called clearing the cervical spine, where a person with a suspected injury is treated as if they have a spinal injury until that injury is ruled out. The objective is to prevent any further spinal cord damage. People are immobilized at the scene of the injury until it is clear that there is no damage to the highest portions of the spine.[25] This is traditionally done using a device called a long spine board and hard collar.

    Once at a hospital and immediate life-threatening injuries have been addressed, they are evaluated for spinal injury, typically by x-ray or CT scan. Complications of spinal cord injuries include neurogenic shockrespiratory failurepulmonary edemapneumoniapulmonary emboli and deep venous thrombosis, many of which can be recognized early in treatment and avoided. SCI patients often require extended treatment in an intensive care unit.[26]

    Techniques of immobilizing the affected areas in the hospital include Gardner-Wells tongs, which can also exert spinal traction to reduce a fracture or dislocation.[27]

    One experimental treatment, therapeutic hypothermia, is used but there is no evidence that it improves outcomes.[28][29] Maintaining mean arterial blood pressures of at least 85 to 90 mmHg using intravenous fluids, transfusion, and vasopressors to ensure adequate blood supply to nerves and prevent damage is another treatment with little evidence of effectiveness.




    Surgery

    Surgery may also be necessary to remove any bone fragments from the spinal canal and to stabilize the spine.[31] Inflammation can cause further damage to the spinal cord, and patients are sometimes treated with a corticosteroid drug such as methylprednisolone to reduce swelling. The drug is used within 8 hours of the injury.[23] This practice is based on the National Acute Spinal Cord Injury Studies (NASCIS) I and II, though other studies have shown little benefit and concerns about side effects from the drug have changed this practice.[32][33] A food dye, brilliant blue G, has also been shown to have some effect at reducing inflammation after spinal injury.[34][35]Methylprednisolone is not longer recommended in the treatment of acute spinal cord injury.

    Steroids

    High dose methylprednisolone may improve outcomes if given within 6 hours of injury.[37] However, the improvement shown by large trials has been small, and comes at a cost of increased risk of serious infection or sepsis due to the immunosuppressive qualities of high-dose corticosteroids. Methylprednisolone is not longer recommended in the treatment of acute spinal cord injury.

    Rehabilitation

    When treating a patient with a SCI, repairing the damage created by injury is the ultimate goal. By using a variety of treatments, greater improvements are achieved, and, therefore, treatment should not be limited to one method. Furthermore, increasing activity will increase his/her chances of recovery.[39]
    The rehabilitation process following a spinal cord injury typically begins in the acute care setting. Physical therapists, occupational therapists, social workers, psychologists and other health care professionals typically work as a team under the coordination of a physiatrist to decide on goals with the patient and develop a plan of discharge that is appropriate for the patient’s condition.
    In the acute phase physical therapists focus on the patient’s respiratory status, prevention of indirect complications (such as pressure sores), maintaining range of motion, and keeping available musculature active.[40] Also, there is great emphasis on airway clearance during this stage of recovery.[41] Following a spinal cord injury, the individual’s respiratory muscles become weak and, in turn, the patient is unable to cough.[42] This results in an accumulation of secretions within the lungs.[42] Physical therapy treatment for airway clearance may include manual percussions and vibrations, postural drainage,[41] respiratory muscle training, and assisted cough techniques.[42] With regards to cough techniques, patients are taught to increase their intra-abdominal pressure by leaning forward to induce cough and clear mild secretions.[42] The quad cough technique is done with the patient lying on their back and the therapist applies pressure on their abdomen in the rhythm of the cough to maximize expiratory flow and mobilize secretions.[42] Manual abdominal compression is another effective technique used to increase expiratory flow which later improves cough.[41] Other techniques used to manage respiratory dysfunction following spinal cord injury include respiratory muscle pacing, abdominal binder, ventilator- assisted speech, and mechanical ventilation.[42]
    Depending on the Neurological Level of Impairment (NLI), the muscles responsible for expanding the thorax, which facilitate inhalation, may be affected. If the NLI is such that it affects some of the ventilatory muscles, more emphasis will then be placed on the muscles with intact function. For example, the intercostal muscles receive their innervation from T1 - T11, and if any are damaged, more emphasis will need to placed on the unaffected muscles which are innervated from higher levels of the CNS. As SCI patients suffer from reduced total lung capacity and tidal volume [43] it is pertinent that physical therapists teach SCI patients accessory breathing techniques (e.g. apical breathing, glossopharyngeal breathing, etc.) that typically are not taught to healthy individuals.

    Outcome measures

    The Functional Independence Measure (FIM) is an assessment tool that aims to evaluate the functional status of patients throughout the rehabilitation process following a stroke,traumatic brain injury, spinal cord injury or cancer.[44] Its area of use can include skilled nursing facilities and hospitals aimed at acute, sub-acute and rehabilitation care. It serves as a consistent data collection tool for the comparison of rehabilitation outcomes across the health care continuum.[44] Furthermore, it aims to allow clinicians to track changes in the functional status of patients from the onset of rehab care through discharge and follow-up. The FIM’s assessment of degree of disability depends on the patient’s score in 18 categories, focusing on motor and cognitive function. Each category or item is rated on a 7-point scale (1 = <25% independence; total assistance required, 7 = 100% independence).[44] As such, FIM scores may be interpreted to indicate level of independence or level of burden of care.

    Prognosis


    Spinal cord injuries frequently result in at least some incurable impairment even with the best possible treatment. In general, patients with complete injuries recover very little lost function and patients with incomplete injuries have more hope of recovery. Some patients that are initially assessed as having complete injuries are later reclassified as having incomplete injuries.

    The place of the injury determines which parts of the body are affected. The severity of the injury determines how much the body will be affected. Consequently, a person with a mild, incomplete injury at the T5 vertebrae will have a much better chance of using his or her legs than a person with a severe, complete injury at exactly the same place in the spine.

    Recovery is typically quickest during the first six months, with very few patients experiencing any substantial recovery more than nine months after the injury.[45]


    Tetraplegia (quadriplegia)


    The ASIA motor score (AMS) is a 100 point score based on ten pairs of muscles each given a five point rating. A person with no injury should score 100. In complete tetraplegia, a recovery of nine points on this scale is average regardless of where the patient starts. Patients with higher levels of injury will typically have lower starting scores.[45]

    In incomplete tetraplegia, 46 percent of patients were able to walk one year after injury, though they may require assistance such as crutches and braces. These patients had similar recovery in muscles of the upper and lower body. Patients who had pinprick sensation in the sacral dermatomes such as the anus recovered better than patients that could only sense a light touch.


    Paraplegia


    Holly Koester incurred a spinal injury as a result of a motor vehicle accident and is now a wheelchair racer.
    In one study on 142 individuals after one year of complete paraplegia, none of the patients where the initial injury was above the ninth thoracic vertebra (T9) were able to recover completely. Less than half, 38 percent, of the studied subjects had any sort of recovery. Very few, five percent, recovered enough function to walk, and those required crutches and other assistive devices, and all of them had injuries below T11. A few of the patients, four percent, had what were originally classified as complete injuries and were reassessed as having incomplete injuries, but only half of that four percent regained bowel and bladder control.[45]
    Of the 54 patients in the same study with incomplete paraplegia 76 percent were able to walk with assistance after one year. On average, patients improved 12 points on the 50 point lower extremity motor score (LEMS) scale. The amount of improvement was not dependent on the location of the injury, but patients with higher injuries had lower initial motor scores and correspondingly lower final motor scores. A LEMS of 50 is normal, and scores of 30 or higher typically predict ability to walk.

    Epidemiology

    Spinal injury can occur without trauma. Many people suffer transient loss of function ("stingers") in sports accidents or pain in "whiplash" of the neck without neurological loss and relatively few of these suffer spinal cord injury sufficient to warrant hospitalization. The prevalence of spinal cord injury is not well known in many large countries. In some countries, such as Sweden and Iceland, registries are available. In the United States, the incidence of spinal cord injury has been estimated to be about 40 cases (per 1 million people) per year or around 12,000 cases per year.[46][47] The most common causes of spinal cord injury are motor vehicle accidents, falls, violence and sports injuries.[47] The average age at the time of injury has slowly increased from a reported 29 years of age in the mid-1970s to a current average of around 40. Over 80% of the spinal injuries reported to a major national database occurred in males.[48] In the United States there are around 250,000 individuals living with spinal cord injuries.[24][49] In China, the incidence of spinal cord injury is approximately 60,000 per year.


    Research directions


    Scientists are investigating many promising avenues for treatment of spinal cord injury. Numerous articles in the medical literature describe research, mostly in animal models, aimed at reducing the paralyzing effects of injury and promoting regrowth of functional nerve fibers.[51] Despite the devastating effects of the condition, commercial funding for research investigating a cure after spinal cord injury is limited, partially due to the small size of the population of potential beneficiaries.[citation needed] Some experimental treatments, such as systemic hypothermia, have been performed in isolated cases in order draw attention to the need for further preclinical and clinical studies to help clarify the role of hypothermia in acute spinal cord injury.[52] Despite the limitation on funding, a number of experimental treatments such as local spine cooling and oscillating field stimulation have reached controlled human trials,[53][54]

    Advances in identification of an effective therapeutic target after spinal cord injury have been newsworthy, and considerable media attention is often drawn towards new developments in this area. However, aside from methylprednisolone, none of these developments have reached even limited use in the clinical care of human spinal cord injury in the U.S.[55]


    Stem cells


    Around the world, proprietary centers offering stem cell transplants and treatment with neuroregenerative substances are fueled by glowing testimonial reports of neurological improvement. It is also evident that when stem cells are injected in the area of damage in the spinal cord, they secrete neurotrophic factors, and these neurotrophic factors help neurons and vessels grow, thus helping repair the damage.[56][57][58] Bone Marrow Stem cells especially the CD34+ cells have been found to be relatively more in men compared to women in the reproductive age group among spinal cord injury patients.[21]

    In 2009 the FDA approved the country's first human trial on embryonic stem cell transplantation into patients suffering from varying levels of traumatic spinal cord injury.[59] The trial however came to a halt in November 2011 when the company, which was financing the trial, announced the discontinuation of the trial due to financial issues.[60] It is important to note that only financial issues led to the trial being discontinued and not any scientific or ethical reasons.[61]

    Other than stem cells, transplantation of tissues such as olfactory ensheathing mucosa have been shown to produce beneficial effects in spinal cord injured rats.[62]
    Independent validation of the results of the various stem cell treatments is lacking.[63][64] However, current approaches on cell and tissue based therapies' for clinical application for spinal cord injury need to establish the underlying efficacy and mechanisms.


    Engineering approaches      
                                                                              

    Recent approaches have used various engineering techniques to improve spinal cord injury repair. The general hypothesis of this is that bridging the lesion site using a growth permissive scaffold may promote axonal extension and in turn improve behavioral function. Engineered treatments are ideal for spinal cord injury repair because they do not induce an immune response like biological treatments and they are easily tunable and reproducible. In-vivo administration of hydrogels or self-assembling nanofibers has been shown to promote axonal sprouting and partial functional recovery.[65][66] In addition, administration of carbon nanotubes has shown to increase motor axon extension, decrease the lesion volume, and not induce neuropathic pain.[67] In addition, administration of poly-lactic acid microfibers has shown that topographical guidance cues alone can promote axonal regeneration into the injury site.[68] However, all of these approaches induced modest behavioral or functional recovery suggesting that further investigation is necessary.


    BCI

    Recent research shows that combining brain–computer interface and functional electrical stimulation can restore voluntary control of paralyzed muscles. A study with monkeys showed that it is possible to directly use commands from the brain, bypassing the spinal cord and enable limited hand control and function.